Optical Coherence Tomography (OCT) is a fundamentally new type of optical imaging modality. OCT performs high-resolution, cross-sectional tomographic imaging of the internal microstructure in materials and biologic systems by measuring backscattered or back reflected light. OCT images are two-dimensional data sets which represent the optical backscattering in a cross-sectional plane through the tissue. Image resolutions of 1 to 15 µm can be achieved one to two orders of magnitude higher than conventional ultrasound. Imaging on the OCT can be performed in situ and in real time. The unique features of this technology enable a broad range of research and clinical applications. OCT, imaging the internal cross-sectional microstructure of tissues using measurements of optical backscattering or back reflection, was first demonstrated in the early nineties. OCT imaging was performed in vitro in the human retina and in atherosclerotic plaque as examples of imaging in transparent, weakly sca Read More